CleveMed Blogs

CleveMed is currently working with the Center for Neurological Restoration at the Cleveland Clinic to monitor motor symptoms during and after Deep Brain Stimulation surgery. To learn more about DBS, click here. Currently, motor symptoms are evaluated during multiple times during DBS surgery to determine if the optimal electrode placement has been determined. Kinesia is being used to evaluate if better methods are available for measuring these symptoms to decrease the duration of the surgery, which can last for hours while the patient is fully conscious, and increase patient comfort. One potential application is to have the patient wear the device while their motor symptoms are being evaluated. The output of Kinesia could then be used as an objective measure from which to base the movement of the electrode.

In addition to the evaluations performed during the surgery, patients need to return to the clinic post surgery to optimize the stimulator settings once the surgical location is completely healed. Here, a nurse or clinician will evaluate the motor symptoms and adjust parameters of the stimulator such as frequency, amplitude and pulse width. As the settings are adjusted, the patient completes an upper extremity evaluation and this is sometimes completed multiple times, which can result in fatigue and therefore, not the most appropriate settings. Here, Kinesia can be worn by the patient while they complete these exams and the output of the device can be correlated to the most optimal stimulator settings. This can decrease the length of time of the visit, as well as increase patient comfort. If the device is able to suggest actual setting parameters, stimulator tuning can be completed in a typical clinician’s office instead of having the patient go to specialty movement disorder centers.

Sleep disordered breathing includes a group of disorders, such as obstructive and central sleep apnea, that are characterized by repeated arousals from sleep as a result of a cessation in breathing, causing highly fragmented and poor quality sleep. Many studies point to a strong link between sleep disordered breathing (SDB) and a number of disorders, particularly cardiovascular disease. Several other studies are finding that adverse surgical outcomes are more frequent in patients with sleep apnea, as both anesthesia and surgery exacerbate airway instability and affect homeostasis in that patient population.

Dr. Nancy Foldvary from Cleveland Clinic Foundation suggests that patients with sleep apnea may be at increased risk for postoperative complications with a greater need for intensive monitoring. Since SDB is a complicating factor in many surgeries, the ability to conveniently conduct a sleep study in those settings can improve the peri-operative management of care, particularly for bariatric and cardiac surgery patients who have high prevalence of obstructive sleep apnea (OSA) (Another potential application for wireless PSG is to diagnose those inpatients with cardiovascular disease who are also suspected of having OSA).

Dr. Nancy Collop with John Hopkins University summarizes that there is an urgent need to improve the diagnosis of sleep disordered breathing in surgical patients in order to avoid complications intraoperatively and postoperatively.

This post draws from the opinions of experts featured in the following news article: CleveMed receives $2.3 million in NIH funding for inpatient diagnosis of sleep disorders in cardiovascular surgery patients